Ecofriendly and Sustainable Pharmaceutical Primary Packaging Materials of Solid Dosage Form

Abstract

The selection of appropriate paper-based materials for pharmaceutical primary packaging is crucial to ensure protection, stability, and compliance with regulatory standards. Various paper types, including butter paper, bleached kraft paper, glassine paper, glossy paper, cellophane paper, and Whatman paper, were evaluated based on key parameters such as thickness, tensile strength, folding endurance, water absorption, water permeability, GSM, and moisture content. Among these, glassine paper was identified as the most suitable material, as its properties closely matched the standard requirements for pharmaceutical-grade packaging. Despite its advantages, glassine paper exhibits limitations in terms of moisture resistance, mechanical strength, and barrier properties. To enhance its functionality and performance, coating techniques were explored to develop an eco-friendly paper-based packaging material for solid dosage forms. These coatings aim to improve moisture resistance, increase mechanical durability, and enhance barrier properties, making the material more effective for pharmaceutical applications. The development of such sustainable packaging aligns with the growing demand for environmentally friendly alternatives while ensuring the safety and stability of pharmaceutical products. This study provides a framework for optimizing paper-based packaging solutions in compliance with pharmaceutical packaging standards.